TIRZEPATIDE 10MG KIT

TIRZEPATIDE 10mg KIT INCLUDES:

TIRZEPATIDE 10mg VIAL, 2mL RECONSTITUTION WATER, AND 4 INSULIN SYRINGES

ONE VIAL = 4 DOSES (25 UNITS EACH DOSE) ONE MONTH SUPPLY – 1 DOSE/WEEK

WHAT IS TIRZEPATIDE?

TIRZEPATIDE (Pronounced Ter-zep-uh-tide) is a once-weekly injectable dual glucagon-like peptide 1 (GLP-1) receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. It works by increasing insulin production and lowering glucagon secretion as well as targeting areas in the brain that regulate appetite and food intake. A small change in the molecule allows the drug to last weeks in our bodies rather than the natural version our bodies make, which lasts minutes.

HOW DOES TIRZEPATIDE WORK?

Delays how quickly our stomachs digest food which leads to a feeling of fullness and satisfaction with smaller meal sizes, decreased appetite and cravings, absorbing nutrients.

Acts on 2 different receptors, which allows for lower blood sugars, in part by reducing the production of sugar in the liver.

Stimulates insulin production and decreases glucagon production in the liver which lowers blood sugar without an increased risk of hypoglycemia.

It appears to affect leptin, the hormone that tells you that you are full, and ghrelin, the hormone that tells you that you are hungry.

GIP increases energy expenditure, which increases metabolism, resulting in weight loss.

In a 2022 study, participants lost an average of 22% of their body weight.

POTENTIAL HEALTH BENEFITS

IMPROVED BLOOD SUGAR CONTROL: Tirzepatide enhances insulin secretion and reduces glucagon levels, leading to better regulation of blood glucose levels. This helps in achieving optimal glycemic control in individuals with type 2 diabetes.

WEIGHT LOSS: Clinical trials have demonstrated significant weight loss in patients using tirzepatide. The medication slows gastric emptying and reduces appetite, contributing to decreased calorie intake and weight reduction.

CARDIOVASCULAR BENEFITS: By improving glycemic control and promoting weight loss, tirzepatide may reduce cardiovascular risk factors such as high blood pressure and elevated cholesterol levels. Some studies suggest potential benefits in lowering the risk of heart disease.

RENAL PROTECTION: Improved blood sugar control can slow the progression of diabetic nephropathy. Some evidence suggests tirzepatide may have direct beneficial effects on kidney function.

IMPROVED LIPID PROFILE: Tirzepatide has been shown to lower triglyceride levels and increase HDL (good) cholesterol, which contributes to a healthier lipid profile.

POTENTIAL ANTI-INFLAMMATORY EFFECTS: Preliminary research indicates that tirzepatide may have anti-inflammatory properties, which could have additional health benefits, although more studies are needed in this area.

POTENTIAL SIDE EFFECTS

The most common side effects are gastrointestinal (GI) and include nausea, vomiting, constipation, acid reflux, stomach pain, or diarrhea. These less commonly occur with tirzepatide than semaglutide. Occasionally, cyanocobalamin (B12) is added to reduce GI side effects.

May cause loss of muscle if you are not consuming an adequate amount of protein and doing resistance exercise. Glycine supplementation can help prevent muscle loss.

Significant weight loss may cause sagging skin and more pronounced wrinkles. This is not specific to GLP-1 medications. ANYTHING that causes significant weight loss will cause more pronounced wrinkles and sagging skin because the underlying supporting structure of your skin has been stretched out from being overweight. The more overweight you are, the more pronounced this effect is when you lose weight.

RISK OF THYROID C−CELL TUMORS. If you or any family members have been diagnosed with Multiple Endocrine Neoplasia Syndrome Type 2 or Medullary thyroid cancer you should not take Tirzepatide.

May increase the risk of developing pancreatitis. However, previous pancreatitis has not been shown to increase future risk of pancreatitis with GLP-1 medications.

The risk of serious side effects increases in patients with hypoglycemia, kidney problems, and risk of allergic reactions. Increasing at longer intervals helps decrease side effects.

This medication is not insulin and should not be used if you have type 1 diabetes or if you develop diabetic ketoacidosis. Tirzepatide should not be used with any other GLP-1 medications.

If you develop intolerable nausea or vomiting, go back to the previous dose for a few more weeks and try to increase again later. You do not have to increase to the maximum dose. If you are losing weight and not having significant side effects, you can maintain at that dose. If you develop severe constipation or abdominal pain, stop the medication and get evaluated by your PCP or Emergency Dept ASAP. If you develop swelling in your neck or difficulty swallowing, get evaluated by your PCP or Emergency Dept.

STORAGE AND STABILITY FOR RESEARCH PEPTIDES

Vials are shipped as lyophilized powder, requiring no refrigeration during shipping.

In Lyophilized Form:

Stable for up to 3 years in the freezer and 2 years in the refrigerator.

Protect from light.

Once Reconstituted:

Stable for 6 weeks.

Must be refrigerated and kept away from light.

Avoid placing vials in the refrigerator door to prevent degradation from frequent temperature changes.

QUALITY ASSURANCE

The manufacturer ensures quality, safety, and efficacy, complying with regulatory standards.

DOSAGE GUIDELINES

Tirzepatide is given as a weekly subcutaneous injection. SUBCUTANEOUSLY (SQ) means beneath the skin, specifically into the fatty tissue layer just under the dermis.

The starting dose is 2.5mg weekly, and the maximum dose is 15mg weekly. IF 2.5MG DOSAGE IS WORKING FINE FOR YOU, THERE’S NO NEED TO INCREASE DOSAGE. INCREASING DOSAGE CAN CAUSE SIDE EFFECTS. Very few patients require the maximum dosage. The optimal dosage is one in which you are losing weight and don’t have intolerable side effects. This is different for each patient. REDUCE DOSAGE IF YOU EXPERIENCE SIDE EFFECTS.

If you experience intolerable side effects, like nausea and vomiting, go back to the dose you were at before for a week or two and try increasing it again. If intolerable nausea or vomiting persists, just stay at the dose you can tolerate.

AVAILABLE IN

10MG VIAL

ONE VIAL = 4 DOSES (25 UNITS EACH DOSE) ONE MONTH SUPPLY – 1 DOSE/WEEK

20MG VIAL

ONE VIAL = 8 DOSES (25 UNITS EACH DOSE) TWO MONTH SUPPLY – 1 DOSE/WEEK

DOSAGE:

SUBCUTANEOUSLY (SQ) means beneath the skin, specifically into the fatty tissue layer just under the dermis.

WEEK 1-4 DOSE: 2.5mg

INJECT: 0.25ML (25 UNITS) SQ ONCE A WEEK FOR 4 WEEKS

RECONSTITUTION INSTRUCTIONS

IMPORTANT: Follow the instructions below regarding the amount of bacteriostatic water to use when reconstituting the peptide.

Do NOT throw away the vial of bacteriostatic water!!! It is a multiuse vial and can be used for your next order!

10 MG VIAL: INJECT 1ML OF BACTERIOSTATIC WATER INTO THE VIAL (1ML = 100 UNITS).

20 MG VIAL: INJECT 2 ML OF BACTERIOSTATIC WATER INTO THE VIAL (2ML = 200 UNITS)

PEPTIDES AREA NON-REFUNDABLE. PLEASE MAKE YOUR SELECTION CAREFULLY